DIAGNOSIS AND CORRECTION OF COMPLICATIONS OF MODERN PROGRAMMED CHEMOTHERAPY IN ACUTE LEUKEMIA

Acute leukemia is a rapidly progressing hematological malignancy that requires intensive programmed chemotherapy as the main treatment approach. Despite significant advances in modern chemotherapeutic protocols, treatment is often associated with a wide range of complications, including myelosuppression, infectious complications, cardiotoxicity, hepatotoxicity, and metabolic disturbances. Early diagnosis and timely correction of these adverse effects are essential for improving treatment outcomes and patient survival. This article reviews the main complications of modern programmed chemotherapy in acute leukemia, discusses diagnostic approaches for early detection, and outlines current strategies for their correction and management. Emphasis is placed on a multidisciplinary approach to minimize treatment-related toxicity while maintaining therapeutic efficacy.